4-AcO-MiPT crystals

4-AcO-MiPT crystals – More information

4-Acetoxy-N-methyl-N-isopropyltryptamine (abbreviated 4-AcO-MiPT and also known as mipracetin) is a synthetic psychedelic tryptamine. It is the acetylated form of 4-HO-MiPT (also known as miprocin) and is a higher homolog of 4-AcO-DMT, 4-AcO-MET and 4-AcO-DET. These substances are commonly hypothesized to act primarily as prodrugs for their respective hydroxylated counterparts (e.g. 4-HO-DMT, 4-HO-MET and 4-HO-DET), although there is on-going debate as to whether they possess their own innate activity.

There is very little information on the human pharmacology or toxicity of 4-AcO-MiPT, although analytical methods have been developed for its detection. Today it is either used recreationally or as an entheogenic substance and is typically acquired through the use of online research chemical vendors. It remains relatively uncommon and has very little history of human usage.

clinical data

4-AcO-MiPT dosage table

4-AcO-MiPT effect progress

Chemistry

4-AcO-MiPT, or 4-Acetoxy-N-isopropyl-N-methyltryptamine, is a synthetic indole alkaloid molecule of the tryptamine class. Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R₃ to an amino group via an ethyl side chain. 4-AcO-MiPT is substituted at R₄ of its indole heterocycle with an acetoxy (AcO) functional group CH₃COO−. It also contains isopropyl and methyl chains bound to the terminal amine R_N of its tryptamine backbone (MiPT).

4-AcO-MiPT is the N-substituted methisopropyl homologue of 4-HO-DMT (psilocin). 4-AcO-MiPT is the acetate ester analog of MiPT and the N-substituted methisopropyl analog of 4-AcO-DMT.

Toxicity

The toxicity and long-term health effects of recreational 4-AcO-MiPT use do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because 4-AcO-MiPT is a research chemical with very little history of human usage.

Anecdotal evidence suggests that there are no negative health effects attributed to simply trying the drug by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.

It is strongly recommended that one use harm reduction practices when using this drug.

Tolerance

4-AcO-MiPT is not habit-forming and the desire to use it can actually decrease with regular consumption. Like with most psychedelics, it is most often thought to be self-regulating.

Tolerance to the effects of 4-AcO-MiPT are built almost immediately after ingestion. After that, it takes about 3 days for the tolerance to be reduced to half and 7 days to be back at baseline (in the absence of further consumption). 4-AcO-MiPT presents cross-tolerance with all psychedelics, meaning that after the consumption of 4-AcO-MiPT all psychedelics will have a reduced effect.

Legal status

Due to its relative obscurity, the possession and sale of 4-AcO-MiPT is unscheduled in most countries.

References