ALD-52 blotters 100 µg

ALD-52 blotters 100 µg – More information

1-Acetyl-N,N-diethyllysergamide (also known as ALD-52, 1-Acetyl-LSD, 1A-LSD, 1A-LAD, and mistakenly as Orange Sunshine) is a lesser-known psychedelic substance of the lysergamide class that produces LSD-like psychedelic effects when administered. It is structurally related to psychedelic lysergamides like LSD and 1P-LSD and is reported to produce largely indistinguishable effects.

ALD-52 was originally discovered by Albert Hofmann in his study of LSD analogs, but it did not enter mainstream awareness until the 1960s Western youth counterculture. ALD-52 gained public notoriety when it was supposedly distributed as LSD in the 1960s under the now-famous name “Orange Sunshine.” This was later disproven (see section below).

Alexander Shulgin touches briefly on the subject of ALD-52 in the commentary section of LSD-25 in the book TiHKAL (“Tryptamines I have Known and Loved”). His writings are based on second-hand accounts which state that doses in the 50-175 µg range result in various effects that are not particularly distinct from LSD. His reports indicate that it produces less visual distortion than with LSD as well as less anxiety and tenseness, while also being somewhat less potent than LSD. Another report found the two substances to be indistinguishable.

As with LSD itself, ALD-52 does not meet the criteria to be considered addictive or toxic by the scientific community. Nevertheless, unpredictable adverse reactions such as anxiety, paranoia, delusions and psychosis are always possible, particularly among those who are predisposed to psychiatric disorders. While these negative reactions or “bad trips” can often be attributed to factors like user inexperience or improper preparation of set and setting, they are known to happen spontaneously among even highly experienced users as well. It is highly advised to approach this very potent, long-lasting hallucinogenic substance with the proper amount of preparation, and harm reduction practices if using it.

clinical data

ALD-52 dosage table

ALD-52 effect progress

History and culture

In 1968 and 1969, a famous batch of LSD known as “Orange Sunshine” was synthesized by Nick Sands and Tim Scully and made widely available in California. This “Orange Sunshine” was long held by the hippie generation to be ALD-52 until 2005, when it was revealed by Nick Sands that “Orange Sunshine” was just a particularly well made batch of LSD dosed at 300 micrograms per unit. This was confirmed by Tim Scully in a 2017 Reddit AMA, where Scully explained that the claim that “Orange Sunshine” was technically not LSD arose from an “ill-advised desperate defense strategy that failed miserably” during his trial for LSD manufacture.

Chemistry

ALD-52, or 1-Acetyl-N,N-diethyllysergamide, is a semisynthethic molecule of the lysergamide chemical class. ALD-52 is a substituted derivative of lysergic acid. ALD-52’s structure contains four rings, a bicyclic hexahydroindole fused to a bicyclic quinoline group. This core structure of ALD-52 is an ergoline derivative, and has tryptamine and phenethylamine structures embedded within it. ALD-52 contains a N,N-diethylcarboxamide functional group bound to R₈ of the chemical structure. It is additionally substituted at carbon 6 with a methyl group.

ALD-52 is homologous to 1P-LSD, which contains a propionyl group bound to CH₃CO- instead of the acetyl group bound to the same location. It is unknown how these differences account for differences in the two compound’s activity.

Toxicity

The toxicity and long-term health effects of recreational ALD-52 use do not appear to have been studied in any scientific context and the exact toxic dose is unknown. This is because ALD-52 is a research chemical with a very limited history of human use.

Anecdotal evidence from people within the community who have tried ALD-52 suggests that there are no negative health effects attributed to simply trying the drug by itself at low to moderate doses and using it very sparingly (although nothing can be completely guaranteed). Independent research should always be conducted to ensure that a combination of two or more substances is safe before consumption.

As with other psychedelic substances, there are relatively few physical side effects that have been reported associated with acute ALD-52 exposure. Although no formal studies have been conducted, it is likely that as with LSD itself, ALD-52 is able to be considered non-addictive, with an extremely low toxicity relative to dose. It is also likely that as with LSD, there are little to no negative physical, cognitive, psychiatric or other toxic consequences associated with acute ALD-52 exposure.

However, as with LSD and psychedelics in general, it is possible that ALD-52 can act as a potential trigger for those with underlying psychiatric conditions. Those with a personal or family history of mental illness are generally advised not to use this substance, particularly outside of a supervised medical setting.

It is strongly recommended that one uses harm reduction practices when using this substance.

Tolerance

Although no formal studies have been conducted, it is not unreasonable to assume that like LSD itself, ALD-52 is not habit-forming and that the desire to use it can actually decrease with use.

Tolerance to the effects of ALD-52 are built almost immediately after ingestion. After that, it takes about 5-7 days for the tolerance to be reduced to half and 14 days to be back at baseline (in the absence of further consumption). ALD-52 presents cross-tolerance with all psychedelics, meaning that after the use of ALD-52 all psychedelics will have a reduced effect.

Overdose

The LD₅₀ of ALD-52 is unknown. Adverse psychological reactions are common especially at higher doses. Some of these include anxiety, delusions, panic attacks and more rarely seizures. Medical attention is usually only needed if suspected of severe psychotic episodes or “fake acid” (such as 25i-NBOMe or DOB). Administration of benzodiazepines or antipsychotics can help to relieve the negative cognitive effects.

Legal status

ALD-52 is currently a gray area compound within many parts of the world. This means that it is not known to be specifically illegal within most countries, but people may still be charged for its possession under certain circumstances such as under analog laws and with the intent to sell or consume.