25B-NBOMe (also known as Cimbi-36 and 2C-B-NBOMe) is a synthetic psychedelic substance of the phenethylamine chemical class. Likewise, it produces an array of visually-dominant and stimulating psychedelic effects when administered.
Anecdotal reports from users suggest 25B-NBOMe to be an active hallucinogen at a dose of as little as 250–500 µg, making it a similar potency to other phenethylamine derived hallucinogens such as Bromo-DragonFLY.
Additionally, it’s worth noting that compounds of the NBOMe class are not orally active and should therefore be taken sublingually by placing the substance into one’s mouth and allowing it to slowly absorb over a period of 15-30 minutes.
clinical data
Common names | 25B-NBOMe |
Substitutive name | 2C-B-NBOMe, BOM 2-CB, Cimbi-36, New Nexus, Nova |
Systematic name | 2-(4-Bromo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl) methyl]ethanamine |
Psychoactive class | Psychedelic |
Chemical class | Phenethylamine |
dosage table
Threshold | 25 – 50 µg |
Light | 50 – 200 µg |
Common | 200 – 350 µg |
Strong | 350 – 500 µg |
Heavy | 25B-NBOMe can be fatal at heavy doses.[1] |
effect progress
Total | 8 – 12 hours |
Offset | 2 – 4 hours |
After effects | 2 – 6 hours |
Chemistry
25B-NBOMe or 2C-B-NBOMe is a serotonergic N-benzyl derivative of the substituted phenethylamine psychedelic known as 2C-B. 25B-NBOMe is a substituted phenethylamine with methoxy groups CH3O- attached to carbons R2 and R5 as well as a bromine atom attached to carbon R4. It differs from 2C-B structurally through a substitution on the amine (NH2) with a 2-methoxybenzyl (BOMe) group. 25B-NBOMe shares this 2-methoxybenzyl substitution with other chemicals of the NBOMe family. That is the NBOMe addition contains a methoxy ether CH3O- bound to a benzene ring at R2.
Tolerance
Almost immediately after ingestion tolerance occurs, mainly to the effects of 25N-NBOMe. After that, it takes about 3 days for the tolerance to be reduced to half and 7 days to be back at baseline (in the absence of further consumption). 25N-NBOMe presents cross-tolerance with all psychedelics, meaning that after the consumption of 25N-NBOMe all psychedelics will have a reduced effect.
What are NBOMes?
NBOMes is the name for a series of drugs that have hallucinogenic effects. Reports indicate that there are a number of different versions of NBOMe available – all with differing effects. Psychedelics change the way a person perceives the world and can affect all the senses, altering a person’s thinking, sense of time and emotions.
What do they look like?
NBOMes can be in the form of blotting paper (similar to LSD) with images and logos from popular culture, clear liquid, white powder or a pill. NBOMes have a very bitter taste whereas LSD has no taste.
Effects of NBOMes
To clarify:
There is no safe level of drug use. Use of any drug always carries some risk – even prescribed medications can produce unwanted side effects.
Low to moderate doses of NBOMes can produce effects that last between 4 – 10 hours.
As for NBOMes, they affect everyone differently, but reported effects have included:
- seeing and hearing things that aren’t there
- feeling happy and relaxed
- heightened senses (sight, hearing and touch)
- increased sex drive
- feelings of empathy
- large pupils
- memory lapses
- facial flushing, chills, goose bumps
- small increase in heart rate.
Overdose
If you take a large amount or have a strong batch, you might overdose. Whatever happens, always call an ambulance straight away by dialing triple zero (000).
Moreover, be extra careful if you have any of these symptoms. Also, you don’t need to fear police since ambulance officers don’t need to involve them.
- confusion
- difficulty communicating
- nausea
- restless sleep and exhaustion
- paranoia, fear and panic
- agitation and aggression
- rapid spasms in the eye
- difficulty urinating
- rapid heart rate
Also, there have also been reports of deaths as a result of car accidents, suicide and drownings.
Using an NBOMe carries a high risk of overdose due to the small difference between the amount required to produce a high and that which causes overdose. Not knowing the amount contained in the tablet or blotter increases the risk of overdose as it’s easy to take too much.
Taking an NBOMe with other drugs
The effects of mixing an NBOMe with other drugs, including alcohol, prescription medication and over-the-counter medicines are not known. However, reports of people attending emergency departments after taking an NBOMe demonstrate that alcohol and other drugs may contribute to overdose effects.
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