1-Butanoyl-d-lysergic acid diethylamide (also known as 1B-LSD) is a substance of the lysergamide class.
1B-LSD is closely related to LSD and 1P-LSD and is reported to produce near-identical effects.
Little is known about the pharmacology of 1B-LSD, but it likely produces its psychedelic effects by acting on serotonin receptors in the brain.
The original synthesis date of 1B-LSD is unknown. Unlike most research chemicals, 1B-LSD has no prior record in the scientific literature. The first reports of 1B-LSD use surfaced in 2018 following its appearance on the online research chemical market.
User reports indicate that the subjective effects of 1B-LSD are extremely similar to those of 1P-LSD. 1B-LSD is theorized to act as a prodrug for LSD.
The similarities in chemical structure between 1B-LSD and LSD predicts a near-identical effect profile, likely differing mainly in its rate of absorption and duration. Characteristics effects include geometric visual hallucinations, time distortion, enhanced introspection, and ego loss.
Its classical psychedelic effects and favorable tolerability has led it to become popular among novel psychoactive substance users who use it interchangeably with LSD.
It is presumed to have a similar toxicity and risk profile as LSD, although no evidence currently exists to support this. It is highly advised to use harm reduction practices if using this substance.
clinical data
Common names | 1B-LSD |
Substitutive name | 1-Butyryl-d-lysergic acid diethylamide |
Psychoactive class | Psychedelic |
Chemical class | Lysergamide |
dosage table
Threshold | 15 µg |
Light | 25 – 75 µg |
Common | 75 – 150 µg |
Strong | 150 – 300 µg |
Heavy | 300 µg + |
effect progress
Total | 8 – 12 hours |
Offset | 3 – 5 hours |
After effects | 6 – 24 hours |
Chemistry
1B-LSD is a molecule of the lysergamide family. It is similar to LSD and is named for the butyryl group bound to the nitrogen of the polycyclic indole group of LSD.
The tetracyclic ergoline is characteristic of the chemical structure of ergot alkaloids. In contrast to LSD, it has an additional N1-butyryl group. Chemical modifications in the N1 position are among the most frequently performed changes in the ergoline system, as the Indole nitrogen is easily accessible for alkylations or acylations.
What are NBOMes?
NBOMes is the name for a series of drugs that have hallucinogenic effects. Reports indicate that there are a number of different versions of NBOMe available – all with differing effects.
Psychedelics change the way a person perceives the world and can affect all the senses, altering a person’s thinking, sense of time and emotions.
NBOMe drugs are also referred to as a New Psychoactive Substances (NPS) because they are designed to mimic or produce similar effects to common illicit drugs such as LSD.
Other names for NBOMes
N-Bomb, Bom-25, 2C-I-NBOMe, 25-I-NBOMe, 25I, Pandora, Solaris, Divination, wizard and Smiley Paper.
25-I-NBOMe is not the same as 2C-I, however. It is important they are not confused because 25-I-NBOMe is a lot stronger and the effects are felt when only a very small amount is taken. It is therefore much easier to overdose after using 25-I-NBOMe.
There have been reports that NBOMes have also been included in some ecstasy pills.
Other types of commonly used psychedelics
- Ayahuasca
- LSD
- Psilocybin
What do they look like?
NBOMes can be in the form of blotting paper (similar to LSD) with images and logos from popular culture, clear liquid, white powder or a pill. NBOMes have a very bitter taste whereas LSD has no taste.
How are they used?
It was originally thought that 25I-NBOMe was inactive if swallowed, however there have been reports of overdoses occurring after oral administration. As a result the most common methods of taking NBOMe are under the tongue, held in the cheek or snorted.
Effects of NBOMes
To clarify:
There is no safe level of drug use. Use of any drug always carries some risk – even prescribed medications can produce unwanted side effects.
Low to moderate doses of NBOMes can produce effects that last between 4 – 10 hours.
NBOMes affects everyone differently, but reported effects have included:
- seeing and hearing things that aren’t there
- feeling happy and relaxed
- heightened senses (sight, hearing and touch)
- increased sex drive
- feelings of empathy
- large pupils
- memory lapses
- facial flushing, chills, goose bumps
- small increase in heart rate.
There have also been reports of deaths as a result of car accidents, suicide and drownings.
Using an NBOMe carries a high risk of overdose due to the small difference between the amount required to produce a high and that which causes overdose. Not knowing the amount contained in the tablet or blotter increases the risk of overdose as it’s easy to take too much.
Long-term effects
As the use of NBOMes is relatively new, long term effects have not yet been established.
Taking an NBOMe with other drugs
The effects of mixing an NBOMe with other drugs, including alcohol, prescription medication and over-the-counter medicines are not known. However, reports of people attending emergency departments after taking an NBOMe demonstrate that alcohol and other drugs may contribute to overdose effects.
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