2C-B-FLY crystals – More information
2C-B-FLY is a lesser-known novel psychedelic substance of the phenethylamine and benzodihydrodifuran classes that produces an array of psychedelic and entactogenic effects when administered. Reports have characterized its effects profile as possessing features of 2C-B, mescaline and MDA, with a duration of 6–8 hours (or up to 12 hours in larger doses).
2C-B-FLY is a derivative of the 2C-x family of psychedelic phenethylamines, specifically 2C-B, of which it significantly differs from in terms of its potency, metabolism, and potential toxicity. It was first synthesized by Aaron P. Monte in 1996.
Around 2005, 2C-B-FLY appeared and gained some popularity in the online research chemicals market before largely disappearing in October 2009, when a batch of Bromo-DragonFLY was accidentally mislabeled as 2C-B-FLY (Bromo-DragonFLY is dosed in micrograms, where 2C-B-FLY is dosed in milligrams) led to two deaths as a result of taking overdoses of Bromo-DragonFLY meant to be effective doses for 2C-B-FLY. This event led to its immediate withdrawal until around 2016, when it resurfaced on the market again.
Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-B-FLY, and it has little history of human usage. It has no documented history of being sold on the streets and is commercially distributed through online research chemical vendors.
Due to its high potency and sensitive dose-response, many reports also indicate that the effects of this substance should not be seen as a simple substitute for 2C-B. It is highly advised to approach this potent, long-lasting, and unpredictable hallucinogenic substance with the proper amount of precaution and harm reduction practices if choosing to use it.
|Chemical class||Benzodihydrodifuran / Phenethylamine|
2C-B-FLY dosage table
|Threshold||2 – 5 mg|
|Light||5 – 10 mg|
|Common||10 – 18 mg|
|Strong||18 – 25 mg|
|Heavy||25 mg +|
2C-B-FLY effect progress
|Total||7 – 12 hours|
|Offset||2 – 3 hours|
|After effects||6 – 24 hours|
History and culture
2C-B-FLY is a substituted molecule of the phenethylamine and dihydrobenzofuran chemical classes. 2C-B-FLY features a phenyl ring bound to an amino (NH2) group through an ethyl chain and contains a bromine atom attached to carbon R4 of the phenyl ring.
It is an atypical psychedelic phenethylamine which is closely analogous to 2C-B; it is the dihydrofuran analog to 2C-B, where it incorporates the methoxy groups bound to R2 and R5 of 2C-B into five-member dihydrofuran rings fused to the central benzene ring.
2C-B-FLY belongs to a group of phenethylamine derivatives referred to as the FLY compounds, named for their insect-like appearance of two “wing-like” tetrahydrofuran rings fused on the opposite sides of the central benzene ring. The incorporation of the two methoxy groups into the 5 member rings fixes them into the optimum position for binding to the receptors they interact with resulting in an increase in potency compared to the compound’s non-rigid counterpart 2C-B.
The toxicity and long-term health effects of recreational 2C-B-FLY do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because 2C-B-FLY is a research chemical with a very limited history of human usage.
Anecdotal evidence from people within the community who have tried 2C-B-FLY suggests that there are no negative health effects attributed to simply trying the drug by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.
It is strongly recommended that one use harm reduction practices when using this substance.
2C-B-FLY is not habit-forming and the desire to use it can actually decrease with use. It is most often self-regulating.
Tolerance to the effects of 2C-B-FLY are built almost immediately after ingestion. After that, it takes about 3 days for the tolerance to be reduced to half and 7 days to be back at baseline (in the absence of further consumption). 2C-B-FLY presents cross-tolerance with all psychedelics, meaning that after the consumption of 2C-B-FLY all psychedelics will have a reduced effect.