NM-2-AI crystal rocks

NM-2-AI crystal rocks – More information

NM-2-AI (N-methyl-2-aminoindane) is a psychoactive drug and research chemical with stimulant properties of the aminoindane chemical class.

In comparison to the more prevalent close chemical relative known as 2-AI, this compound has a lower potency, a longer duration and very similar effects. Besides this, very little is known about this substance. It has recently become easily accessible through online research chemical vendors where it is sold as a designer drug.

clinical data

NM-2-AI dosage table

NM-2-AI effect progress

Chemistry

NM-2-AI, or N-methyl-2-AI, is the N-methylated derivative of 2-Aminoindane and is analogous to amphetamine. It features the R₃ terminal carbon of the propane chain of amphetamine bound to the benzene ring. This creates an indane, a bicycle containing a benzene ring fused to a pentane ring. The amino group 2-AI shares with amphetamine is bound to R₂ of the indane group. N-methyl-2-AI contains a methyl group bound to the amino group R_N (for which it is named).

Toxicity

The toxicity and long-term health effects of recreational NM-2-AI use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because NM-2-AI has very little history of human usage. Anecdotal evidence from people who have tried NM-2-AI within the community suggest that there do not seem to be any negative health effects attributed to simply trying this drug at low to moderate doses by itself and using it sparingly (but nothing can be completely guaranteed).

It is strongly recommended that one use harm reduction practices when using this drug.

Tolerance

As with other stimulants, the chronic use of NM-2-AI can be considered moderately addictive with a high potential for abuse and is capable of causing psychological dependence among certain users. When addiction has developed, cravings and withdrawal effects may occur if a person suddenly stops their usage.

Tolerance to many of the effects of NM-2-AI develops with prolonged and repeated use. This results in users having to administer increasingly large doses to achieve the same effects. After that, it takes about 3 – 7 days for the tolerance to be reduced to half and 1 – 2 weeks to be back at baseline (in the absence of further consumption). NM-2-AI presents cross-tolerance with all dopaminergic stimulants, meaning that after the consumption of NM-2-AI all stimulants will have a reduced effect.

Psychosis

Abuse of compounds within the stimulant class at high dosages for prolonged periods of time can potentially result in a stimulant psychosis that may present with a variety of symptoms (e.g., paranoia, hallucinations, or delusions). A review on treatment for amphetamine, dextroamphetamine, and methamphetamine abuse-induced psychosis states that about 5–15% of users fail to recover completely. The same review asserts that, based upon at least one trial, antipsychotic medications effectively resolve the symptoms of acute amphetamine psychosis.

Legal issues

NM-2-AI is currently believed to be a grey area compound within most parts of the world. This means that it is not known to be specifically illegal within any country but people may still be charged for its possession under certain circumstances such as under analogue laws and with intent to sell or consume.